Caplets for Fast Migraine Relief Excedrin Migraine Caplets for Migraine Headache Relief provide migraine relief fast, making Excedrin Migraine the number 1 neurologist recommended OTC treatment for migraines (1). Excedrin works in 3 ways to relieve migraines: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance the pain relief effect. Available in convenient caplet form, this powerful migraine medicine delivers a specialized triple action formula containing two pain relievers and an amplifier. These Excedrin caplets combine aspirin and acetaminophen with caffeine to provide migraine relief, including migraine...